阿胶补血膏的药效学研究_阿胶补血膏的作用.docx
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1、阿胶补血膏的药效学研究_阿胶补血膏的作用 摘要:目的视察阿胶补血膏灌胃给药对小鼠失血性贫血及非特异性免疫功能的影响。方法将50只贫血模型小鼠随机分为5组,每组10只,分别为阳性比照复方阿胶浆组(12.5 mL/kg),阿胶补血膏大剂量组(12.5 g/kg)、中剂量组(6.25 g/kg)、小剂量组(3.13 g/kg)及模型比照组,各组小鼠分别灌胃赐予不同剂量的药物,进行视察。结果阿胶补血膏小鼠灌胃给药可使失血性贫血小鼠血红蛋白及红细胞明显回升,与模型比照组比较有显著性差异;可明显增加碳粒廓清速率,对小鼠非特异性免疫有增加作用。结论该药可治疗失血性贫血小鼠,提高非特异性免疫功能。 关键词:阿
2、胶补血膏;失血性贫血;非特异性免疫 中图分类号:R973+.3文献标识码:A文章编号:1672-979X(2007)01-0034-02 Pharmacodynamics Study of E-jiao Hematinic Ointment ZENG Qing-hua1, DING Shi-lun2 (1.School of Agriculture, Liaocheng University, Liaocheng 252059, China; 2.Shandong Fujiao Inc., Jinan 250400, China) Abstract:Objective To observe t
3、he curative effect of E-jiao hematinic ointment on posthemorrhagic anemia and nonspecific immunity of mice given by intragastric administration.Methods 50 anemia mice were divided into 5 groups randomly with 10 in each group, which are positive control compound E-jiao slurry group(12.5 mL/kg), E-jia
4、o hematinc ointment high dose group(12.5 g/kg), middle dose group(6.25 g/kg), low dose group(3.13 g/kg)and model control group, respectively. Mice of each group were given by intragastric administration, and observation was made. Results E-jiao hematinic ointment could make the hemoglobin and erythr
5、ocyte of the posthemorrhagic anemia mice increase obviously, which had significant difference to the model control group; it could also increase the clearance rate of carbon particle, which had an enhancement effect of nonspecific immunity of mice. Conclusion The drug has the curative effect on post
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