食管癌放射治疗设定照射野范围的分析研究.pdf
《食管癌放射治疗设定照射野范围的分析研究.pdf》由会员分享,可在线阅读,更多相关《食管癌放射治疗设定照射野范围的分析研究.pdf(3页珍藏版)》请在得力文库 - 分享文档赚钱的网站上搜索。
1、 临床应用食管癌放射治疗设定照射野范围的分析研究王霞1,高献书21.河北医科大学附属第一医院放疗科,河北 石家庄 0500312.河北医科大学附属第四医院放疗科,河北 石家庄 050011Analysis of the radiation fields in radiotherapy for esophageal carcinomaWA NG Xia1,GAO Xian-shu21.Departmentof Radiotherapy,No.1 Af f iliated Hospital of Hebei Medical Univercity,Shijiazhuang 050031,P.R.Ch
2、ina2.Departmentof Radiotherapy,FouthAf f iliated H ospital of H ibei Medical University,Shij iazhuang 050011,P.R.China【摘要】目的:分析照射野与预后的关系,为模拟定位时更好地确定照射范围提供参考。方法:回顾分析 2000 年 4 月 2001 年4 月在河北医科大学第四医院放疗科进行后程加速超分割放疗的符合入组条件的食管癌患者 102例,计算常规设野时野长和野宽外扩的范围,分析与生存率的关系。结果:常规模拟定位设野长度外扩的范围按照中位值分为 4 1 2 cm 和 4 1 2
3、cm 两组,412 cm 组 1、2、3 和 4 年生 存率 分别 为76 1 0%、50 1 0%、2813%和 21 12%;412 cm组 分 别 为69 10%、55 1 4%、4812%和38 1 0%。两组总体生存率差异无统计学意义,V2=2 1 15,P=0114。设野宽度外扩的范围按照中位值分为 118 cm 和 1 1 8 cm 两组,1 1 8 cm 组 1、2、3 和 4 年生 存率为64 1 0%、46 1 0%、3610%和 29 13%;118 cm组为 76 1 9%、53 1 9%、42 1 3%和 31 1 5%。两组总体 生存率 差异 无统 计学 意义,V2
4、=0162,P=0 1 73。结论:设野长度外扩的范围对总体生存率的影响差异无统计学意义,但 412 cm 组在生存方面显示了一定的优越性。设野宽度外扩的范围对总体生存率的影响差异无统计学意义,但 1 1 8 cm 组在生存方面显示了一定的优越性。中华肿瘤防治杂志,2006,13(5):372-374ABS TRACT OBJECTIVE:To design suitable radiation fields for e-sophagealcarcinoma for the patients treatedby late course acceleratedhy-perfractionatio
5、n radiotherapy and analyse the relationship between radia-tion fields and prognosis.METH ODS:From April,2000 to April,2001,102 patients were selected accordding to the qualification,who were trea-ted by late course accelerate hyperfractionation radiotherapy schedule.The relationship betweenthe radia
6、tion fields and the overall survivalrateswas analysed.RESULTS:The patients were divided into two groups ac-cording to median length 4 12 cm.One-year survival rates in 4 1 2 cmgroup,and 412 cm group were 76 1 0%,69 1 0%,2-year survival rateswere 50 1 0%,55 1 4%,3-year survival rates were 28 1 3%,48 1
7、2%,4-year survival rates were 21 12%,38 10%,There was no significantdiffence in the two groups,V2=2 115,P=0 114.The patients weredivided into two groups according to median width 118 cm.One-yearsurvival rates in 1 1 8 cm group,and 1 1 8 cm group were 64 10%,76 1 9%,2-year survival rates were 46 1 0%
8、,53 19%,3-year survivalrates were 36 10%,42 1 3%,4-yearsurvival rates were 29 13%,31 1 5%.There was no significant difference in the two groups,V2=0 1 62,P=0 173.CONCLUSIONS:Overall survival rates were comparedin different lengths that the radiation fields covered beyond the tumourmargin longitudina
9、lly rates and different widths that radiation fields ex-tended beyond the tumour volume.There was no significant difference,although survival rate was higher in 4 12 cm group thanthat in 4 12cm group,the survival rate was higher in 1 1 8 cm group than that in 1 18 cm group.Chin J Cancer Prev T reat,
10、2006,13(5):372-374【关键词】食管肿瘤/放射疗法;放射疗法/方法;预后 KEYWORDS esophageal neoplasms/radiotherapy;radiotherapy/methods;prognosis【中图分类号】R735.2 【文献标识码】A 【文章编号】1673-5269(2006)05-0372-03【第一作者简介】王霞,女,河北石家庄人,硕士,主治医师,主要从事食管癌的临床研究工作。Tel:86-311-83055732 E-mail:byhwx 【通讯作者简介】高献书,男,河北石家庄人,教授,博士生导师,主要从事食管癌基础与临床研究工作。E-mail
- 配套讲稿:
如PPT文件的首页显示word图标,表示该PPT已包含配套word讲稿。双击word图标可打开word文档。
- 特殊限制:
部分文档作品中含有的国旗、国徽等图片,仅作为作品整体效果示例展示,禁止商用。设计者仅对作品中独创性部分享有著作权。
- 关 键 词:
- 食管癌 放射 治疗 设定 照射 范围 分析研究
限制150内