SCI写作高大上句型1000例-2.pdf
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1、1 SCI写作高大上句型写作高大上句型1000例例101200101、Theactivationof.inresponseto.signallingisrequiredfor.,andtheresultspresentedabovesuggestthat.isacomponentofthissignalingcascade102、Totestthishypothesis,weperformed.Thisfeaturemightexplainthefactthat103、Invivoexperimentssuggestthat.Thisissupportedbythefactthatdeplet
2、ionof.withtheaidofRNAinterference(RNAi)attenuatesRhoactivationinresponsetoTofurtherexplorethemechanismof.function,weexaminedtheinteractionsbetween.and,.104、Toinvestigatethefunctionof.105、Wetestedthispredictionbyanalyzing.106、Several studies have demonstrated that.pathway controls during.development,
3、andthatactivationof.isanindispensablestepinthisprocess107、This differencemay reflect thefact thatcommon but variant molecularmechanismmaybeinvolvedin108、Fivelinesofevidenceindicatethat.ledustopredictandverifythat109、Itwillbeinterestingtoinvestigatewhether.hasanimportantfunctioninthisprocess.110、.use
4、dasatraditionalChinesemedicineforcenturies,offerstherapeuticpotentialforcardiovascularandotherdiseases.,extractedfromtherootextractofrhubarbhassparkedincreasinginterestfortherapeuticapplication.111、Itwaspostulatedthat.Thereforethepresentstudywasdesignedtostudytheeffectof.onVSMCsproliferationinducedb
5、yAngII,andtheexpressionof.112、.hasbeenimplicatedin.underliningitsimportanceincardiovasculardisease113、XXXprovidedapossibleavenueforinterferencewithVSMCsproliferation.114、Themajorfindingofthisworkshowedthat.115、Thepresentstudyprovidedavaluablenovelinsightintomolecularmechanismsof.inhibitedVSMCsprolif
6、erationinducedby.2 116、ToverifythatemodinmediatedeffectsonVSMCswerenotaconsequenceofcytotoxicity,LDH activity was determined as a parameter of cytotoxicity insupernatantsofemodinandAngIItreatedcells.Consistentwiththelightmicroscopeobservations,LDHactivityinsupernatantsoftreatedanduntreatedcellsremai
7、nedunchanged.Sotheinhibitoryeffectwasmainlyduetoaninhibitionofcellproliferationratherthantoadirectcytotoxiceffect.117、Further evidence was provided that.played a crucial role in thecardioprotectivepropertiesof.118、Thepresentstudywasundertakentoelucidatetheeffectofthe.and.incombinationonXXX.Thepresen
8、tstudieswereundertakentoinvestigatethepotentialeffectof.andtoexplorethecellularmechanismofcrosstalkoftheAT1receptorandstatininvascularsmoothmusclecells(VSMCs).119、Thepresentstudyexploredthepossibilitythat.120、Collectively,thesefactsandspeculationssuggestthat121、Inordertoascertainacausalrelationshipb
9、etween122、Unfortunately,wecouldnotcompletelyexcludetheinvolvementof123、Collectively,thesefactsandspeculationssuggestthat124、Althoughmolecularmechanismsinvolvedinhavenotbeenfullyclarified,125、Insummary,thepresentstudydemonstratesthat126inourconditionswecouldnotruleoutapossibleinvolvementofthisinmedia
10、ting127、Insupportofthishypothesis,ithasbeenshownthat.128、Thispotentiationeffectindirectlysuggeststhateachagonistusesadifferentsignalingpathway129、Most likely this is due to an accumulative effect of both drugsinhibitingactivity.130、Itistemptingtospeculatethatthebeneficialeffectofmayalsobedueto3 inhi
11、bitionof.131、TherelevanceandtheexactmechanismsbywhichaspirinaffectsSRBI,CD36andABCA1invitroremaintobedetermined,asdoestheroleofCD36expressioninantiatherogenicconditions.132、Inthepresentstudy,first,weinvestigatedtheexpressionofPPARsinBAEC,andsubsequently,examinedwhetherPPARactivatorsmodifyTNFaandPMAi
12、nducedLOX1expressioninculturedBAEC.133、Ourresultsdonotallowustoexcludetheparticipationofsuchmechanismsinthedownregulationof134、Althoughthepotentialrolesofthisreceptorinatherogenesisarenotyetfullyunderstood,ithasbeensuggestedthat135、Inthecurrentstudy,weinvestigatedtheeffectof.136、Inthelastdecade,itwa
13、srecognizedthatplayapivotalroleinbothearlyandlateatherogenesis137、.arefundamentalplayersinatherogenesissincetheychangethepropertiesofdifferentcellsinvolvedinatherosclerosisandthrombosis138、Thisreviewelucidatesthemajoraspectsconcerning.139、Interestingly,invitroandinvivostudieshaverevealedthat.140、The
14、predominantfunctionof.inatheroscleroticlesionformationisthoughttobeactivationof141、Asweandothershavereported,.werethefirsttoshowinvivothat142、RecentreportshaveestablishedSMCsasamajorplayerintheinitiationoftheatheroscleroticprocessinadditiontotheirroleinthrombusformationafterplaqueruptureinlateathero
15、sclerosis.143、Infact,thereisincreasingevidencethat.144、Althoughitisnotfullyclearwhichreceptorisresponsibleforthebindingofnativelipoproteins,somedataindicatethat4 145、Theemergingconceptthat.146、It is well knownthatHowever,there are different opinionsconcerningFurthermore,itisstillnotsufficientlyeluci
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